Pentecost is currently the Professor of Photography at the Art Institute of Chicago. She received her BA in 1980 from Smith College and her MFA in 1988 from Pratt Institute. Pentecost completed the Whitney Independent Study Program in 1989. Her interdisciplinary practice interrogates the imaginative and institutional structures that organize divisions of knowledge, focusing on nature, artificiality and food systems. Pentecost has exhibited at the Drawing Center, NY, Whitney Museum of American Art, NY, American Fine Art Gallery, NY, Corcoran Museum, Washington, D.C., Transmediale 05, Berlin. Since 2006, she has worked with Brian Holmes and 16Beaver, organizing a series of seminars in New York and Zagreb. Pentecost was a keynote speaker during the Creative Time Summit at Cooper Union, NY, October 2010. Claire Pentecost's solo exhibition at Higher Pictures, Interior Studies, was held in 2010.